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Validation of the medical outcomes study family and marital functioning measures in SLE patients in Singapore

Departments of Rheumatology and Immunology

K-Y Fong

Department of Medicine, National University of Singapore; and

S-P Chan

Clinical Epidemiology, Tan Tock Seng Hospital

K-H Leong

P-H Feng

S-T Thio

Departments of Rheumatology and Immunology

M-L Boey

Mount Elizabeth Medical Centre, Singapore

Objective: To validate the Medical Outcomes Study Family and Marital Functioning Measures (FMM and MFM) in a multi-ethnic, urban Asian population in Singapore.

Methods: English speaking Chinese, Malay or Indian SLE patients (n ‘ 120) completed a selfadministered questionnaire containing the FFM and MFM at baseline, after 2 weeks and after 6 months. Lupus activity, disease-related damage and quality of life were assessed using the British Isles Lupus Assessment Group (BILAG), Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index and SF-36 Health Survey respectively. Scale psychometric properties were assessed through factor analysis, Cronbach's a, quantifying test-retest differences and known-groups construct validity.

Results: Factor analysis of scores obtained at baseline and after 6 months identified 3 factors corresponding to the FFM (1 factor) and the MFM (2 factors). Both scales showed acceptable internal consistency, with Cronbach's a of 0.95 for the FFM and 0.70 for the MFM. Mean (s.d.) test-retest differences were 7 0.31 (3.82) points for the FFM and 7 0.70 (4.26) points for the MFM. Eleven out of 13 a priori hypotheses relating both the FFM and MFM to demographic, disease and quality of life variables were confirmed, supporting the construct validity of these scales.

Conclusion: The FFM and MFM are valid and reliable measures of family and marital functioning in a multi-ethnic cohort of Asian SLE patients in Singapore.

Key Words: systemic lupus erythematosus • family • quality of life • SF-36 • Asia • Singapore

Lupus, Vol. 8, No. 7, 514-520 (1999)
DOI: 10.1191/096120399678840747


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