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Lupus, Vol. 8, No. 9, 773-774 (1999)
DOI: 10.1191/096120399678841025

Minocycline-induced clinical and biological lupus-like disease

Christophe Tournigand

Service de MWdecine Interne de la Salpetrire (Pr Herson)

Thierry Genereau

Murielle Prudent

Service de Pediatrie, Centre Hospitalier de Sens, Sens, France

Marie-Claude Diemert

Laboratoire d'Immunochimie, Paris, France

Serge Herson

Olivier Chosidow

Service de MWdecine Interne de la Salpetrire (Pr Herson)

A 14-year-old girl developed maculopapular rash, myalgias, arthralgias and myocarditis with elevated anti-nuclear and anti-double-stranded DNA antibodies. She was taking minocycline for acne and all symptoms resolved when this treatment was stopped. The patient has no evidence of disease one year after onset of symptoms. Clinicians should be aware of minocycline's responsibility in inducing lupus-like disease.

Key Words: drug-induced lupus • minocycline • anti-double-stranded DNA antibodies


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Minocycline in Acne Is Still an Issue
Arch Dermatol, September 1, 2000; 136(9): 1143 - 1145.
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