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Lupus
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Letter

Overwhelming septic cavernous sinus thrombosis in a woman after combination of high-dose steroid and intravenous cyclophosphamide therapy for lupus nephritis

Ying-Chou Chen

Tiang-Tsai Cheng

Hung-Min Lai

Chien-Hui Wu

Division of Rheumatology and Immunology, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan

There are many treatment methods for lupus nephritis, including high-dose steroids, pulse methylprednisolone, and cyclophosphamide therapy. In cyclophosphamide therapy, there can be some side effects such as nausea, vomiting, and infection. We report on a case receiving a combination of high dose steroid and intravenous cyclophosphamide. Following this, she developed a fever and a protruding right eye, and septic cavernous sinus thrombosis was diagnosed. This complication had never been reported in a patient with systemic lupus erythematosus, and related literature is reviewed.

Lupus, Vol. 9, No. 1, 78-79 (2000)
DOI: 10.1177/096120330000900116


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Rheumatology (Oxford)Home page
R. R. Sivaraj, O. M. Durrani, A. K. Denniston, P. I. Murray, and C. Gordon
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[Abstract] [Full Text] [PDF]



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