Lupus

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Arora, M
Right arrow Articles by Srivastava, L M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Arora, M
Right arrow Articles by Srivastava, L M
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Lupus, Vol. 9, No. 2, 127-131 (2000)
DOI: 10.1191/096120300678828154

Expression of complement regulatory proteins in diffuse proliferative glomerulonephritis

M Arora

Department of Biochemistry, All India Institute of Medical Sciences, New Delhi-110029, India

R Arora

School of Life Sciences, Jawahar Lal University, New Delhi, India

S C Tiwari

Department of Nephrology, All India Institute of Medical Sciences, New Delhi-110029, India

N Das

L M Srivastava

Department of Biochemistry, All India Institute of Medical Sciences, New Delhi-110029, India

This study assessed the expression of complement receptor 1 (CR1), decay accelerating factor (DAF) and membrane inhibitor of reactive lysis (CD59) on the erythrocytes and glomerulus of diffuse proliferative glomerulonephritis (DPGN) of systemic lupus erythematosus (SLE) patients using flow cytometry and immunofluorescence techniques to elucidate their role in the pathogenesis of DPGN. Expression of CR1 on the erythrocytes and glomerulus of DPGN patients was reduced compared with expression in normal subjects. However, expression of DAF and CD59 was increased on both erythrocytes and glomerulus of DPGN patients, suggesting the generation of a protective response against complement-mediated injury.

Key Words: complement receptor 1 (CR1) • decay accelerating factor (DAF) • membrane inhibitor of reactive lysis (CD59) • diffuse proliferative lupus glomerulonephritis (DPGN) • erythrocytes(E)


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 LupusHome page
I Garcia-Valladares, Y Atisha-Fregoso, Y Richaud-Patin, J Jakez-Ocampo, E Soto-Vega, D Elias-Lopez, E Carrillo-Maravilla, J Cabiedes, A Ruiz-Arguelles, and L Llorente
Diminished expression of complement regulatory proteins (CD55 and CD59) in lymphocytes from systemic lupus erythematosus patients with lymphopenia
Lupus, September 1, 2006; 15(9): 600 - 605.
[Abstract] [PDF]

Home page
 Clin. Microbiol. Rev.Home page
A. L. Servin
Pathogenesis of Afa/Dr Diffusely Adhering Escherichia coli
Clin. Microbiol. Rev., April 1, 2005; 18(2): 264 - 292.
[Abstract] [Full Text] [PDF]

Home page
 LupusHome page
J. Verma, V. Arora, V. Marwaha, A. Kumar, and N. Das
Association of leukocyte CR1 gene transcription with the disease severity and renal involvement in systemic lupus erythematosus
Lupus, April 1, 2005; 14(4): 273 - 279.
[Abstract] [PDF]

Home page
 LupusHome page
B Sivasankar, A K Dinda, S C Tiwari, L M Srivastava, and N Das
Modulation of urinary CR1 in systemic lupus erythematosus
Lupus, April 1, 2004; 13(4): 228 - 233.
[Abstract] [PDF]