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Extensive lymphadenopathy as the first clinical manifestation in systemic lupus erythematosus

Eleni Andreopoulou

Departments of Internal Medicine, Ioannina, Greece

Maria K Bai

Pathology, Medical School, University of Ioannina, Ioannina, Greece

Moses Elisaf

Departments of Internal Medicine, Ioannina, Greece

Alexandros A Drosos

Department of Internal Medicine, Medical School, University of Ioannina, 451 10 Ioannina, Greece

Lymphadenopathy (LAP) is a frequent sign of systemic lupus erythematosus (SLE). The lymph nodes are usually soft, nontender, varying in size from 0.5 cm to several centimeters. However, generalized LAP in SLE is extremely rare, while to our knowledge, the presentation of extensive LAP with blocks of retrosternal, mesenteric, and retroperitoneal nodes has not been previously reported as the first clinical manifestation of the disease. In this report we describe a patient with extensive LAP and active SLE and we point out that generalized LAP should be included among the clinical findings indicating disease activity in SLE patients.

Key Words: systemic lupus erythematosus • lymphadenopathy • Kikuchi disease

Lupus, Vol. 9, No. 2, 140-143 (2000)
DOI: 10.1191/096120300678828037


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