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Acute optic neuropathy and transverse myelopathy in patients with antiphospholipid antibody syndrome: Favorable outcome after treatment with anticoagulants and glucocorticoids

Department of Medicine, Sectionof Rheumatology, Louisiana State University Medical Center, New Orleans, LA, USA

M D Conway

Department of Ophthalmology, Louisiana State University Medical Center, New Orleans, LA, USA

H J Robertson

Department of Radiology, Louisiana State University Medical Center, New Orleans,LA, USA

L R Espinoza

Department of Medicine, Section of Rheumatology, Louisiana State University Medical Center, New Orleans, LA, USA

W A Wilson

Department of Medicine, Section of Rheumatology, 1542 Tulane Avenue Box T4M4, New Orleans, LA 70123 9, USA. Tel (/ 1) (504)5684630; Fax: (/ 1) (504) 568 4642

We describe two patients with established antiphospholipidsyndrome, who during periods of subtheraputic anticoagulation, developed acute optic neuropathy and transverse myelopathy. Treatment with optimal anticoagulation and high dose glucocorticoids was followed by resolution of the neurologic deficits.

Key Words: transverse myelopathy • optic neuropathy • antiphospholipid antibodies • Sjogren's syndrome • antiphospholipid syndrome • multiple sclerosis

Lupus, Vol. 9, No. 4, 307-310 (2000)
DOI: 10.1191/096120300680198944


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