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Lupus
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A case of progressive systemic sclerosis complicated by massive pleural effusion with elevated CA125

M Funauchi

Third Department of Internal Medicine, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan. Tel: (/81) 723 660221 X3128; Fax: (/81) 723 683732

S Ikoma

H Yu

M Sugiyama

M Ohno

K Kinoshita

K Hamada

A Kanamaru

Third Department of Internal Medicine, Kinki University School of Medicine, Osaka Japan

A tumor marker, CA125, is known to increase in the serum or other body fluids in various malignancies such as ovarian cancer. Here we present a case of progressive systemic sclerosis (PSS) with massive pleural effusion, in which CA125 in the serum and pleural fluid were elevated. The serum level of CA125 decreased in accordance with the change of the pleural effusion. CA125 level may be an indicator for the activity of serositis in some cases with collagen vascular diseases.

Key Words: CA125 • progressive systemic sclerosis • pleuritis

Lupus, Vol. 9, No. 5, 382-385 (2000)
DOI: 10.1191/096120300678828334


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Home page
Postgrad. Med. J.Home page
S F Hussain, J Grayez, A Grigorian, and J T Green
Massive pleural effusion and marked increase of CA-125
Postgrad. Med. J., May 1, 2004; 80(943): 300 - 301.
[Abstract] [Full Text] [PDF]



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