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Lupus
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Erythema nodosum associated with antiphospholipid antibodies: a report of three cases

L Nekhlyudov

M Gradzka

Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA

A M Conti-Kelly

Department of Medicine, Saint Mary's Hospital, Waterbury, CT, USA

T P Greco

Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA; Department of Medicine, Saint Mary's Hospital, Waterbury, CT, USA

Erythema nodosum is a dermatologic condition characterized by painful, erythematous nodules on the anterior surfaces of the lower extremities. Its association with a variety of conditions has been previously described. We present three cases of erythema nodosum in patients with elevated anticardiolipin antibodies. In one patient, a temporal relationship was seen in the simultaneous detection of antibodies and skin lesions. We propose an association between erythema nodosum and the antiphospholipid antibody syndrome (APS).

Key Words: antiphospholipid antibodies • APS • erythema nodosum

Lupus, Vol. 9, No. 8, 641-645 (2000)
DOI: 10.1191/096120300678828767


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